An Inhibitor of Protein Arginine Methyltransferases, 7,7′-Carbonylbis(azanediyl)bis(4-hydroxynaphthalene-2-sulfonic acid (AMI-1), Is a Potent Scavenger of NADPH-Oxidase–Derived Superoxide
نویسندگان
چکیده
منابع مشابه
An inhibitor of protein arginine methyltransferases, 7,7'-carbonylbis(azanediyl)bis(4-hydroxynaphthalene-2-sulfonic acid (AMI-1), is a potent scavenger of NADPH-oxidase-derived superoxide.
The methylation of proteins is an important post-translational mechanism that has been established to influence the activity of nuclear and nucleic acid binding proteins. Much less is known about the importance of protein methylation in the regulation of cytosolic proteins. Increased methylation of proteins is observed in cardiovascular disease and occurs in conjunction with elevated production...
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ژورنال
عنوان ژورنال: Molecular Pharmacology
سال: 2009
ISSN: 0026-895X,1521-0111
DOI: 10.1124/mol.109.061077